ILLUMINATING PATHOGEN-HOST INTIMACY THROUGH OPTOGENETICS.

Illuminating pathogen-host intimacy through optogenetics.

Illuminating pathogen-host intimacy through optogenetics.

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The birth and subsequent evolution of optogenetics has resulted in an unprecedented advancement in our understanding of the brain.Its outstanding success does usher wider applications; however, the tool remains still largely relegated to neuroscience.Here, we introduce selected aspects of optogenetics Ball - Catcher - Kits with potential applications in infection biology that will not only answer long-standing questions about intracellular pathogens (parasites, bacteria, viruses) but Toners also broaden the dimension of current research in entwined models.In this essay, we illustrate how a judicious integration of optogenetics with routine methods can illuminate the host-pathogen interactions in a way that has not been feasible otherwise.

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